Understanding how immunizations stimulate protection begins with a deep dive into the mechanisms of vaccine action & immune response. Cellular and humoral components interact in finely tuned sequences, with antigen presentation, cytokine signaling, and T and B cell activation forming the foundation of long-term immunity. These mechanisms vary depending on the nature of the vaccine platform and the immune status of the recipient. Research now extends beyond classical pathways, incorporating innate immune training, epigenetic reprogramming, and memory imprinting. A more nuanced grasp of these biological processes enables the design of next-generation vaccines that are both targeted and durable. Ongoing investigations also explore how variations in host genetics, microbiota, and previous exposures affect immunologic outcomes. Clarifying these relationships is key to addressing population-level variability in vaccine efficacy and safety, ultimately guiding more personalized and effective immunization strategies.
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Nanoscopic SubATVax™ adjuvanted vaccines against influenza A types H3N2, H1N1 and influenza type B for subcutaneous administration
David Craig Wright, D4 Labs, LLC, United States
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy