Vaccine Safety Surveillance and Pharmacovigilance

Ongoing vaccine safety surveillance and pharmacovigilance are vital for identifying rare adverse events and maintaining public trust post-licensure. Passive systems like VAERS and active surveillance networks collect real-world data to assess vaccine performance and detect safety signals. Advances in digital health tools, big data analytics, and electronic health records enable rapid signal detection and response. Pharmacovigilance practices also involve lot-release monitoring, risk management plans, and collaboration across regulatory agencies. Transparent communication of findings is critical to addressing vaccine hesitancy and misinformation. As more novel platforms enter the market, vaccine safety surveillance and pharmacovigilance must evolve to match the complexity of emerging technologies while preserving rigorous scientific standards and community engagement.