Vaccine adjuvants are substances added to vaccines to enhance the body's immune response to the intended antigen. The primary goal is to improve the vaccine's efficacy by promoting a stronger, longer-lasting, and more robust immune reaction. Common adjuvants include aluminum salts (alum), which have been used for decades and are found in various vaccines. Other adjuvants include oil-in-water emulsions, liposomes, and virosomes. These adjuvants often stimulate a more significant production of antibodies and activate immune cells, contributing to a heightened defense against pathogens. Adjuvants play a crucial role in enhancing vaccine effectiveness, especially in situations where a strong immune response is needed, such as in certain populations or against rapidly evolving pathogens. They enable the use of lower vaccine doses while still achieving optimal protection. Research in vaccine adjuvants focuses on understanding their mechanisms of action, optimizing formulations, and ensuring safety. Balancing enhanced immunogenicity with minimal side effects is crucial in developing effective and well-tolerated vaccines for a variety of infectious diseases.
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Nanoscopic SubATVax™ adjuvanted vaccines against influenza A types H3N2, H1N1 and influenza type B for subcutaneous administration
David Craig Wright, D4 Labs, LLC, United States
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy