Viral replication is a complex process by which viruses use host cell machinery to produce new viral particles. The life cycle generally involves several key stages: attachment, penetration, uncoating, replication and transcription, translation, assembly, and release. Upon attaching to specific host cell receptors, viruses penetrate the cell either through direct fusion with the cell membrane or via endocytosis. Once inside, the virus undergoes uncoating, freeing its genetic material. Replication and transcription involve the synthesis of viral RNA or DNA using host cell machinery. Viral proteins are then produced through translation of the viral genome. These components are assembled into new virus particles, often in specialized cellular compartments. Release can occur through cell lysis, where the host cell is destroyed, or through a more subtle process called budding, where new virus particles exit the cell without causing immediate cell death. Understanding viral replication is crucial for developing antiviral strategies, including drugs that target various stages of the viral life cycle. Research in this area continues to uncover the intricacies of host-virus interactions, aiding the development of interventions to combat viral infections.
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Nanoscopic SubATVax™ adjuvanted vaccines against influenza A types H3N2, H1N1 and influenza type B for subcutaneous administration
David Craig Wright, D4 Labs, LLC, United States
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy