Virulence factors are components of pathogens that contribute to their ability to cause disease, and targeting these factors is a central strategy in vaccine development. Vaccines often aim to neutralize or block the action of virulence factors, such as bacterial toxins, surface proteins, or enzymes that enable pathogens to invade host cells or evade the immune system. By preventing the pathogen from expressing these harmful factors, vaccines can significantly reduce the severity of infection or prevent it altogether. For example, vaccines against bacterial diseases like tetanus, diphtheria, and whooping cough focus on neutralizing the toxins that cause damage in the body. Researchers continue to identify new virulence factors for targeting, especially for emerging or drug-resistant pathogens, expanding the range of diseases that can be controlled through vaccination. By focusing on virulence factors, vaccines can provide highly specific and effective protection with fewer side effects.
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Nanoscopic SubATVax™ adjuvanted vaccines against influenza A types H3N2, H1N1 and influenza type B for subcutaneous administration
David Craig Wright, D4 Labs, LLC, United States
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy